Last update
3/25/2026
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.1
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Thiamin (as Thiamine Mononitrate)
25 mg
2,083%
Riboflavin
25 mg
1,923%
Niacin (as Nicotinic Acid)
25 mg NE§
156%
Vitamin B6 (as Pyridoxine HCl [25 mg] and Pyridoxal 5-Phosphate [10 mg])
35 mg
2,059%
Folate (400 mcg as (6S)-5-MTHF [from (6S)-5-Methyltetrahydrofolate Glucosamine Salt)
680 mcg DFE‡
170%
Vitamin B12 (as Methylcobalamin)
100 mcg
4,167%
Biotin (as d-Biotin)
300 mcg
1,000%
Pantothenic Acid (as Calcium D-Pantothenate)
100 mg
2,000%
Choline (as Choline Bitartrate)
50 mg
9%
Pantethine
25 mg
†
Inositol
50 mg
†
Top Medical Research Studies
9
We sought to understand how intramuscular vitamin B12 could help alleviate low back pain in patients with mechanical lumbago. In a rigorous study involving 60 participants, we compared the effects of vitamin B12 to a placebo.
Our findings indicated that those receiving the vitamin reported significantly less pain and disability, as measured by a visual scale and disability questionnaire. Notably, those on vitamin B12 also used less paracetamol than the placebo group.
Overall, our study confirmed that vitamin B12 can be effective for treating low back pain without nutritional deficiency.
Our findings indicated that those receiving the vitamin reported significantly less pain and disability, as measured by a visual scale and disability questionnaire. Notably, those on vitamin B12 also used less paracetamol than the placebo group.
Overall, our study confirmed that vitamin B12 can be effective for treating low back pain without nutritional deficiency.
Read More
8
This study evaluated the effects of intramuscular methylcobalamin injections on chronic low back pain.
In a rigorously designed double-blinded, randomized controlled trial, 60 patients were divided into treatment and placebo groups.
We observed significant improvements in pain and disability scores among those receiving methylcobalamin compared to the placebo.
Additionally, the treatment was found to be safe, with only minor side effects reported.
In a rigorously designed double-blinded, randomized controlled trial, 60 patients were divided into treatment and placebo groups.
We observed significant improvements in pain and disability scores among those receiving methylcobalamin compared to the placebo.
Additionally, the treatment was found to be safe, with only minor side effects reported.
Read More
8
Vitamin B complex aids back pain relief
We examined how well celecoxib and a combined vitamin B complex worked for people experiencing lower back pain, comparing them with meloxicam.
Our findings indicated that celecoxib, especially when paired with Neuromultivit (a vitamin B complex), showed improved effectiveness in relieving both acute and chronic back pain.
Interestingly, while meloxicam offered similar initial pain relief, celecoxib was found to be superior for long-term recovery and quality of life improvements.
This suggests that adding vitamin B to treatment could enhance outcomes for those suffering from chronic lower back pain.
Our findings indicated that celecoxib, especially when paired with Neuromultivit (a vitamin B complex), showed improved effectiveness in relieving both acute and chronic back pain.
Interestingly, while meloxicam offered similar initial pain relief, celecoxib was found to be superior for long-term recovery and quality of life improvements.
This suggests that adding vitamin B to treatment could enhance outcomes for those suffering from chronic lower back pain.
Read More
Most Useful Reviews
9
Back improvement
7 people found this helpful
On the recommendation of a trusted person, I took these vitamins as I was often experiencing back issues that necessitated painful injections. Since starting these capsules, my reliance on injections has vanished, and my overall back condition has significantly improved.
Read More
9
Resolved back pain
This powerful complex resolved my back pain (pinched, inflamed nerves) within just three days.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.1
- All Researches
9
Combination therapy shows effectiveness
We set out to explore whether a rehabilitation program combined with specific supplements could effectively treat sciatica in young patients. Our study involved 128 individuals who were divided into three groups: one receiving both rehabilitation and supplements, one only with rehabilitation, and one with only supplements.
After treatment, the group with both rehabilitation and supplements showed significant improvement in pain relief and overall quality of life compared to the others. While the supplement-only group didn’t perform as well, this combination approach proved beneficial, particularly in reducing pain and enhancing stability.
After treatment, the group with both rehabilitation and supplements showed significant improvement in pain relief and overall quality of life compared to the others. While the supplement-only group didn’t perform as well, this combination approach proved beneficial, particularly in reducing pain and enhancing stability.
Read More
We explored how effective vitamin B complex, alongside nonsteroidal anti-inflammatory drugs, is in treating back pain. Our study involved 70 patients divided into two groups, one receiving a vitamin B complex blend and the other a different pain relief combination.
Both groups showed improvement, but the first group experienced a clearer reduction in pain levels over time. By the third visit, they reported significantly less discomfort compared to the second group. Though both treatments were effective, the vitamin B complex showed a more pronounced impact on pain relief and patient satisfaction.
Both groups showed improvement, but the first group experienced a clearer reduction in pain levels over time. By the third visit, they reported significantly less discomfort compared to the second group. Though both treatments were effective, the vitamin B complex showed a more pronounced impact on pain relief and patient satisfaction.
Read More
9
We sought to understand how intramuscular vitamin B12 could help alleviate low back pain in patients with mechanical lumbago. In a rigorous study involving 60 participants, we compared the effects of vitamin B12 to a placebo.
Our findings indicated that those receiving the vitamin reported significantly less pain and disability, as measured by a visual scale and disability questionnaire. Notably, those on vitamin B12 also used less paracetamol than the placebo group.
Overall, our study confirmed that vitamin B12 can be effective for treating low back pain without nutritional deficiency.
Our findings indicated that those receiving the vitamin reported significantly less pain and disability, as measured by a visual scale and disability questionnaire. Notably, those on vitamin B12 also used less paracetamol than the placebo group.
Overall, our study confirmed that vitamin B12 can be effective for treating low back pain without nutritional deficiency.
Read More
9
Vitamin B complex effective for pain
We examined how Dolo-Neurobion, a blend of essential B vitamins and an analgesic, affects acute lumbosacral pain. In a study of 53 patients, we found that this treatment yielded good to excellent results in 77.4% of cases, while 15.1% experienced moderate effects. The approach combined initial parenteral dosing with continuation through oral intake, and any necessary antibiotics were also used. Most notably, we observed no significant side effects, making Dolo-Neurobion a promising option for back pain relief linked to pelvic organ issues.
Read More
8
We explored how combining dexamethasone with vitamin B12 could impact early recovery from back and leg pain after a specific spine surgery called percutaneous endoscopic interlaminar discectomy (PEID).
In our study, patients were divided into two groups: one received only the surgery, while the other got epidural injections of both medications during surgery.
Results showed that the combined treatment significantly reduced pain and inflammation, leading to better early recovery outcomes. This suggests that using this combination might be a great option for patients undergoing this type of surgery.
In our study, patients were divided into two groups: one received only the surgery, while the other got epidural injections of both medications during surgery.
Results showed that the combined treatment significantly reduced pain and inflammation, leading to better early recovery outcomes. This suggests that using this combination might be a great option for patients undergoing this type of surgery.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Back improvement
7 people found this helpful
On the recommendation of a trusted person, I took these vitamins as I was often experiencing back issues that necessitated painful injections. Since starting these capsules, my reliance on injections has vanished, and my overall back condition has significantly improved.
Read More
9
Resolved back pain
This powerful complex resolved my back pain (pinched, inflamed nerves) within just three days.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- He C, Li J, Hu W, Xiao B, Fan T, et al. Effects of dexamethasone combined with vitamin B12 on percutaneous endoscopic interlaminar discectomy early outcomes: a randomized controlled trial. J Orthop Surg Res. 2024;19:733. 10.1186/s13018-024-05210-z
- Scaturro D, Vitagliani F, Tomasello S, Sconza C, Respizzi S, et al. Combined Rehabilitation with Alpha Lipoic Acid, Acetyl-L-Carnitine, Resveratrol, and Cholecalciferolin Discogenic Sciatica in Young People: A Randomized Clinical Trial. Medicina (Kaunas). 2023;59. 10.3390/medicina59122197
- Antonen EG, Kruchek MM, Nikitina MV. [Evaluation of the effectiveness of treatment of patients with nonspecific pain syndrome in the lower back with celecoxib and a combined preparation of B vitamins]. Zh Nevrol Psikhiatr Im S S Korsakova. 2022;122:65. 10.17116/jnevro202212208165
- Barantsevich ER, Yakovlev AA, Gavrilova EA, Gavrichenko AV, Pushkarev MS, et al. [Study of the clinical efficacy and safety of the scheme of step therapy of nonsteroidal anti-inflammatory drugs and a complex of B vitamins in patients with low back pain]. Zh Nevrol Psikhiatr Im S S Korsakova. 2021;121:67. 10.17116/jnevro202112110167
- Nava-Mesa MO, Aispuru Lanche GR. [Role of B vitamins, thiamine, pyridoxine, and cyanocobalamin in back pain and other musculoskeletal conditions: a narrative review]. Semergen. 2021;47:551. 10.1016/j.semerg.2021.01.010
- Calderon-Ospina CA, Nava-Mesa MO, Arbeláez Ariza CE. Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis. Pain Med. 2020;21:766. 10.1093/pm/pnz216
- Khabirov FA, Khaibullin TI, Granatov EV. [Evaluation of efficiency and safety of adding neuromultivit to basic therapy of vertebrogenic radiculopathy]. Zh Nevrol Psikhiatr Im S S Korsakova. 2017;117:38. 10.17116/jnevro201711710138-43
- Chiu CK, Low TH, Tey YS, Singh VA, Shong HK. The efficacy and safety of intramuscular injections of methylcobalamin in patients with chronic nonspecific low back pain: a randomised controlled trial. Singapore Med J. 2011;52:868. PubMed
- Levin OS, Moseĭkin IA. [Vitamin B complex (milgamma) in the treatment of vertebrogenic lumbosacral radiculopathy]. Zh Nevrol Psikhiatr Im S S Korsakova. 2009;109:30. PubMed
- Mibielli MA, Geller M, Cohen JC, Goldberg SG, Cohen MT, et al. Diclofenac plus B vitamins versus diclofenac monotherapy in lumbago: the DOLOR study. Curr Med Res Opin. 2009;25:2589. 10.3111/13696990903246911
- Mauro GL, Martorana U, Cataldo P, Brancato G, Letizia G. Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study. Eur Rev Med Pharmacol Sci. 2000;4:53. PubMed
- Brüggemann G, Koehler CO, Koch EM. [Results of a double-blind study of diclofenac + vitamin B1, B6, B12 versus diclofenac in patients with acute pain of the lumbar vertebrae. A multicenter study]. Klin Wochenschr. 1990;68:116. PubMed
- Kuhlwein A, Meyer HJ, Koehler CO. [Reduced diclofenac administration by B vitamins: results of a randomized double-blind study with reduced daily doses of diclofenac (75 mg diclofenac versus 75 mg diclofenac plus B vitamins) in acute lumbar vertebral syndromes]. Klin Wochenschr. 1990;68:107. PubMed
- Kunt T. [Complaints in the lumbosacral region and their management with Dolo-Neurobion]. Fortschr Med. 1978;96:299. PubMed
